Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129651 | 0.76 | AKR1C3 (0.45) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14829704 | 0.75 | CES2 (0.47) | HTTCYP2C19RAB9ACYP1A2CYP3A4 | |
| SCHEMBL186133 | 0.73 | CA3 (0.45) | HTTALDH1A1PKM | |
| SCHEMBL10442091 | 0.73 | FFAR4 (0.45) | CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL6036225 | 0.73 | KMT2A (0.38) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9444987 | 0.72 | PKM (0.62) | HTTCYP2C19ALDH1A1NPC1RAB9A | |
| SCHEMBL28396688 | 0.72 | MRGPRX4 (0.49) | CYP2C19ALDH1A1CYP1A2CYP3A4PKM | |
| SCHEMBL9445003 | 0.72 | RAB9A (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL9000255 | 0.71 | FABP3 (0.61) | ALDH1A1FABP3FABP4MPOAKR1C3 | |
| SCHEMBL22853479 | 0.71 | KDM4E (0.52) | HTTCYP2C19FABP3FABP4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647614-B1 | Process for the préparation of 5-fluoro anthranilic acid | HOECHST AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0647614-A1 | Process for the préparation of 5-fluoro anthranilic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-12 | — | — | EP | disclosed |