Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444130 | 0.85 | REN (0.38) | REN | |
| SCHEMBL10443798 | 0.83 | REN (0.55) | REN | |
| SCHEMBL10443715 | 0.83 | REN (0.55) | REN | |
| SCHEMBL10444067 | 0.81 | REN (0.51) | RENCTSL | |
| Hydrochloric Acid SCHEMBL10444382 | 0.81 | REN (0.39) | REN | |
| SCHEMBL11127124 | 0.81 | CTSL (0.51) | RENCTSL | |
| Water SCHEMBL10443597 | 0.80 | REN (0.38) | REN | |
| SCHEMBL10715998 | 0.78 | REN (0.45) | RENCTSL | |
| SCHEMBL10754242 | 0.77 | REN (0.46) | RENCTSL | |
| SCHEMBL10444046 | 0.76 | REN (0.55) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350163-A2 | Renin inhibitory peptides | BEECHAM GROUP PLC (GB) | 1990-01-10 | — | — | EP | disclosed |