Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445431 | 0.87 | ACE (0.53) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL8041086 | 0.84 | CTSL (0.52) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL5711379 | 0.81 | CTSL (0.57) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL5711376 | 0.81 | CTSL (0.57) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL8053336 | 0.78 | CTSL (0.51) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL6348412 | 0.76 | CTSL (0.52) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL6348415 | 0.76 | CTSL (0.52) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL10445830 | 0.75 | USP30 (0.44) | CTSLCTSSCTSKKMT2A | |
| SCHEMBL528464 | 0.73 | ACE (0.76) | CTSLCTSSCTSKACECTRB1 | |
| SCHEMBL111236 | 0.73 | ACE (0.76) | CTSLCTSSCTSKACECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |