Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041030 | 0.86 | USP30 (0.48) | USP30ITGB3ITGA2BCTSLCTSS | |
| SCHEMBL10696299 | 0.83 | USP30 (0.45) | USP30MEN1KMT2AITGB3ITGB1 | |
| SCHEMBL7369942 | 0.81 | GRB2 (0.36) | MEN1KMT2AITGB3ITGAVITGA2B | |
| SCHEMBL7369938 | 0.81 | GRB2 (0.36) | MEN1KMT2AITGB3ITGAVITGA2B | |
| SCHEMBL8058939 | 0.80 | PTPN1 (0.57) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7275364 | 0.76 | CA2 (0.62) | MEN1KMT2AFPR2 | |
| SCHEMBL10445581 | 0.75 | CTSL (0.50) | KMT2ACTSLCTSSCTSK | |
| SCHEMBL7378185 | 0.73 | ITGB3 (0.57) | KMT2AITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL7378190 | 0.73 | ITGB3 (0.57) | KMT2AITGB3ITGB1ITGAVITGA2B | |
| Trifluoroacetic Acid SCHEMBL17894404 | 0.72 | EPHX2 (0.53) | HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |