Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445604 | 0.94 | TRPM8 (0.52) | TRPM8CTSBCTSLCTSSCTSK | |
| SCHEMBL10445671 | 0.87 | CTSL (0.49) | TRPM8CTSBCTSLMEN1KMT2A | |
| SCHEMBL10445814 | 0.85 | SYK (0.46) | F2PLAUPLATTRPM8CTSD | |
| SCHEMBL10432188 | 0.84 | F2 (0.50) | F2PLAUPLATTRPM8CTSB | |
| SCHEMBL7434857 | 0.83 | SYK (0.56) | TRPM8CTSBCTSLCTSSCTSK | |
| SCHEMBL10445815 | 0.79 | CTSS (0.47) | CTSBCTSLCTSSCTSKMEN1 | |
| SCHEMBL5704587 | 0.78 | TRPM8 (0.57) | TRPM8CTSBCTSLCTSSCTSK | |
| SCHEMBL10432189 | 0.78 | TRPM8 (0.53) | TRPM8CTSBCTSLCTSSCTSK | |
| SCHEMBL10432302 | 0.77 | SYK (0.48) | TRPM8CTSL | |
| SCHEMBL9724730 | 0.77 | TRPM8 (0.53) | F2PLAUPLATTRPM8CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |