SCHEMBL1044649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1044650	1.00	PTGES2 (0.45)	PTGES2NFE2L2CCR3GAAMAOA
	SCHEMBL1046098	0.82	KDM4E (0.33)	PTGES2NFE2L2GAAGRIN1GRIN2B
	SCHEMBL1046100	0.82	KDM4E (0.33)	PTGES2NFE2L2GAAGRIN1GRIN2B
	SCHEMBL4292103	0.80	CCR3 (0.41)	PTGES2CCR3GAAGRIN1GRIN2B
	SCHEMBL29822699	0.79	CDK4 (0.51)	PTGES2NFE2L2CCR3GAAMAOA
	SCHEMBL1045015	0.78	KDM4E (0.34)	PTGES2GAAMAOAMAOBGRIN1
	SCHEMBL2098188	0.78	PTGES2 (0.40)	PTGES2NFE2L2CCR3GAAMAOA
	SCHEMBL2098186	0.78	PTGES2 (0.40)	PTGES2NFE2L2CCR3GAAMAOA
	Ethylene SCHEMBL27581062	0.77	ALDH1A1 (0.52)	PTGES2CCR3GAAALDH1A1RXRA
	Formaldehyde SCHEMBL27526817	0.77	ALDH1A1 (0.52)	PTGES2CCR3GAAALDH1A1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.