Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447080 | 0.94 | HTT (0.49) | HTTRECQLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446650 | 0.84 | HTT (0.46) | HTTRECQLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10447033 | 0.84 | UBE2M (0.49) | HTTRECQLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10447346 | 0.84 | TAS1R3 (0.47) | HTTRECQLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9259744 | 0.76 | GAA (0.51) | HTTRECQLSMN1; SMN2MAPTNPC1 | |
| SCHEMBL10447007 | 0.75 | HTT (0.50) | HTTTAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL10446784 | 0.74 | RECQL (0.47) | HTTRECQLTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446762 | 0.72 | UBE2M (0.52) | HTTTAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL9756708 | 0.72 | PKM (0.44) | HTTTAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL10446779 | 0.72 | PKM (0.46) | HTTRECQLTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |