Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447006 | 0.82 | UBE2M (0.46) | RAB9ATAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10446779 | 0.80 | PKM (0.46) | RAB9ATAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL9756708 | 0.80 | PKM (0.44) | RAB9ATAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL10446762 | 0.80 | UBE2M (0.52) | TAS1R3TAS1R1TAS1R2HTTPKM | |
| SCHEMBL10447056 | 0.80 | UBE2M (0.51) | RAB9ATAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL10447090 | 0.80 | HTT (0.45) | RAB9ATAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL10447042 | 0.80 | MEN1 (0.55) | RAB9ATAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL10446648 | 0.79 | UBE2M (0.51) | RAB9ATAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL10446781 | 0.79 | UBE2M (0.47) | RAB9ATAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10447005 | 0.79 | MEN1 (0.52) | RAB9ATAS1R3TAS1R1TAS1R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |