Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 9/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447111 | 0.93 | UBE2M (0.49) | UBE2MDCUN1D1THRBKMT2APOLB | |
| SCHEMBL10447172 | 0.79 | RAB9A (0.41) | UBE2MDCUN1D1THRBKMT2AKDM4E | |
| SCHEMBL10446801 | 0.78 | RAB9A (0.46) | UBE2MDCUN1D1KMT2APOLBRAB9A | |
| SCHEMBL10446671 | 0.76 | P2RX3 (0.49) | UBE2MDCUN1D1KMT2APOLBNPSR1 | |
| SCHEMBL10446624 | 0.75 | UBE2M (0.43) | UBE2MDCUN1D1KMT2APOLBRAB9A | |
| SCHEMBL10446652 | 0.75 | P2RX3 (0.47) | UBE2MDCUN1D1POLBRAB9ANPC1 | |
| SCHEMBL10447056 | 0.73 | UBE2M (0.51) | UBE2MDCUN1D1THRBKMT2APOLB | |
| SCHEMBL9270701 | 0.71 | UBE2M (0.53) | UBE2MDCUN1D1POLBRAB9A | |
| SCHEMBL9270364 | 0.71 | UBE2M (0.52) | UBE2MDCUN1D1POLBRAB9ANPC1 | |
| SCHEMBL9270367 | 0.71 | UBE2M (0.52) | UBE2MDCUN1D1POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |