Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 8/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446676 | 0.90 | HTT (0.43) | RECQLUBE2MDCUN1D1HTTPKM | |
| SCHEMBL10446691 | 0.90 | RECQL (0.44) | RECQLUBE2MDCUN1D1HTTPKM | |
| SCHEMBL10446779 | 0.84 | PKM (0.46) | RECQLUBE2MDCUN1D1HTTPKM | |
| SCHEMBL10447047 | 0.84 | HTT (0.42) | UBE2MDCUN1D1HTTPKMTAS1R3 | |
| SCHEMBL10446784 | 0.84 | RECQL (0.47) | RECQLUBE2MDCUN1D1HTTTAS1R3 | |
| SCHEMBL10446781 | 0.82 | UBE2M (0.47) | UBE2MDCUN1D1HTTPKMTAS1R3 | |
| SCHEMBL10447008 | 0.82 | UBE2M (0.46) | UBE2MDCUN1D1HTTPKMTAS1R3 | |
| SCHEMBL10447012 | 0.81 | HTT (0.39) | UBE2MDCUN1D1HTTPKMTAS1R3 | |
| SCHEMBL10446783 | 0.80 | RAB9A (0.44) | UBE2MDCUN1D1HTTPKMTAS1R3 | |
| SCHEMBL10447033 | 0.80 | UBE2M (0.49) | RECQLUBE2MDCUN1D1HTTTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |