Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448405 | 0.79 | DDB1 (0.41) | ALDH1A1KMT2AHPGDTNKS2HTR2A | |
| SCHEMBL135940 | 0.74 | CA2 (0.40) | SMN1; SMN2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL6253800 | 0.71 | MEN1 (0.32) | KMT2A | |
| SCHEMBL5855954 | 0.67 | SLC6A2 (0.40) | SLC6A3ALDH1A1KDM4EHSD17B10SLC6A2 | |
| SCHEMBL10242244 | 0.67 | SLC6A3 (0.46) | TP53RECQLSMN1; SMN2SLC6A3ALDH1A1 | |
| SCHEMBL16064832 | 0.67 | SLC6A3 (0.46) | TP53RECQLSMN1; SMN2SLC6A3ALDH1A1 | |
| SCHEMBL6414970 | 0.67 | LDHA (0.43) | TP53RECQLSMN1; SMN2SLC6A3ALDH1A1 | |
| SCHEMBL14580255 | 0.66 | TP53 (0.65) | TP53RECQLSMN1; SMN2SLC6A3ALDH1A1 | |
| SCHEMBL28782592 | 0.65 | SLC6A3 (0.47) | TP53RECQLSMN1; SMN2SLC6A3ALDH1A1 | |
| SCHEMBL28542554 | 0.64 | TP53 (0.41) | TP53RECQLSMN1; SMN2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367233-A2 | Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4874876-A | ACYLATING THIOPHENE, REDUCING, HYDROLYZING | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |