SCHEMBL1044880

SCHEMBL1044880

c1ccc(C2=C(c3ccccc3)C(c3ccccc3)=C(c3ccccc3)C2)cc1.c1ccc([Bi](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
CFTR P13569 1/20 0.41
GOPC Q9HD26 1/20 0.41
KMT2A Q03164 1/20 0.41
PTGS2 P35354 10/20 0.39
PTGS1 P23219 7/20 0.39
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ABCB11 O95342 1/20 0.31
MT-CO2 P00403 1/20 0.31
HTR1A P08908 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
MC4R P32245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147807 0.86 CFTR (0.52) ESR1ESR2CFTRGOPCKMT2A
SCHEMBL8197843 0.86 CFTR (0.52) ESR1ESR2CFTRGOPCKMT2A
SCHEMBL868869 0.72 CFTR (0.68) ESR1ESR2CFTRGOPCKMT2A
SCHEMBL219794 0.72 ALDH1A1 (0.40) PTGS2PTGS1ALDH1A1LMNAMAPT
SCHEMBL27585641 0.72 ALDH1A1 (0.40) PTGS2PTGS1ALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL7758771 0.71 CFTR (0.43) ESR1ESR2CFTRGOPCKMT2A
SCHEMBL6151994 0.71 CFTR (0.43) ESR1ESR2CFTRGOPCKMT2A
Hydrochloric Acid SCHEMBL3373258 0.70 CFTR (0.41) ESR1ESR2CFTRGOPCKMT2A
Hydrochloric Acid SCHEMBL3373261 0.70 CFTR (0.46) ESR1ESR2CFTRGOPCKMT2A
Hydrochloric Acid SCHEMBL7760049 0.70 CFTR (0.41) ESR1ESR2CFTRGOPCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272929-B1 Process for improving the adhesion of a material crosslinkable by UV on a substrat COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-08-09 EP disclosed
CN-101950791-B Process for improving the adhesion of a material crosslinkable by UV on a substrate COMMISSARIAT ENERGIE ATOMIQUE 2015-05-13 CN disclosed
US-8475619-B2 Process for improving the adhesion of a UV-crosslinkable material to a substrate COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-07-02 US disclosed
US-20110024034-A1 PROCESS FOR IMPROVING THE ADHESION OF A UV-CROSSLINKABLE MATERIAL TO A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-02-03 US disclosed
CN-101950791-A But be used to improve the adhering method of the crosslinked material of UV to substrate COMMISSARIAT ENERGIE ATOMIQUE 2011-01-19 CN disclosed
EP-2272929-A1 Process for improving the adhesion of a material crosslinkable by UV on a substrat Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2011-01-12 EP disclosed