SCHEMBL8197843

SCHEMBL8197843

c1ccc(C2=C(c3ccccc3)C(c3ccccc3)=C(c3ccccc3)C2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.52
GOPC Q9HD26 1/20 0.52
KMT2A Q03164 1/20 0.50
PTGS2 P35354 9/20 0.46
PTGS1 P23219 6/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
ALDH1A1 P00352 2/20 0.44
ABCB11 O95342 1/20 0.36
MT-CO2 P00403 1/20 0.36
HTR1A P08908 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MC4R P32245 1/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
SLC6A4 P31645 1/20 0.36
PDE4B Q07343 1/20 0.36
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147807 1.00 CFTR (0.52) CFTRGOPCKMT2APTGS2PTGS1
SCHEMBL1044880 0.86 ESR1 (0.42) CFTRGOPCKMT2APTGS2PTGS1
SCHEMBL868869 0.84 CFTR (0.68) CFTRGOPCKMT2APTGS2PTGS1
SCHEMBL6151994 0.83 CFTR (0.43) CFTRGOPCKMT2APTGS2PTGS1
Hydrochloric Acid SCHEMBL7758771 0.83 CFTR (0.43) CFTRGOPCKMT2APTGS2PTGS1
Hydrochloric Acid SCHEMBL3373258 0.81 CFTR (0.41) CFTRGOPCKMT2APTGS2PTGS1
Hydrochloric Acid SCHEMBL7760049 0.81 CFTR (0.41) CFTRGOPCKMT2APTGS2PTGS1
Hydrochloric Acid SCHEMBL3373261 0.81 CFTR (0.46) CFTRGOPCKMT2APTGS2PTGS1
SCHEMBL13191298 0.81 ESR1 (0.49) CFTRGOPCKMT2APTGS2PTGS1
SCHEMBL13191506 0.81 PTGS2 (0.50) CFTRGOPCKMT2APTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3153605-B1 METHOD FOR PRODUCING A LAYERED (SEMI-)CONDUCTIVE MATERIAL UNIV DRESDEN TECH (DE) 2018-07-11 EP claimed
EP-3153605-A1 METHOD FOR PRODUCING A LAYERED (SEMI-)CONDUCTIVE MATERIAL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-04-12 EP claimed
CN-108137748-B Process for preparing polyolefins having one or more pendant functional groups SABIC环球技术有限责任公司 2021-05-04 CN disclosed
CN-108368270-B Process for preparing a polyolefin-based graft copolymer comprising a first functionalized short chain branched polyolefin block and one or more polymer side chains SABIC环球技术有限责任公司 2021-03-02 CN disclosed
CN-108291032-B Process for preparing a polyolefin graft copolymer comprising a first long-chain branched polyolefin block and one or more polymer side chains SABIC环球技术有限责任公司 2021-01-26 CN disclosed
CN-107223138-B Process for preparing polyolefins having one or more end-functionalized branches SABIC环球技术有限责任公司 2020-10-23 CN disclosed
CN-107531829-B Process for preparing a block copolymer comprising a first polyolefin block and a second polymer block and product obtained from said process SABIC环球技术有限责任公司 2020-09-22 CN disclosed
EP-3153605-B1 METHOD FOR PRODUCING A LAYERED (SEMI-)CONDUCTIVE MATERIAL UNIV DRESDEN TECH (DE) 2018-07-11 EP disclosed
EP-3153605-A1 METHOD FOR PRODUCING A LAYERED (SEMI-)CONDUCTIVE MATERIAL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-04-12 EP disclosed
EP-1004604-A2 Catalyst for production of vinyl-based polymer and process for production of vinyl-based aromatic polymer IDEMITSU KOSAN CO., LTD. (JP) 2000-05-31 EP disclosed
US-5858904-A Catalyst for production of vinyl-based polymer and process for production of vinyl-based aromatic polymer IDEMITSU KOSAN CO., LTD. (JP) 1999-01-12 US disclosed
EP-0698619-A1 CATALYST FOR PRODUCING VINYL POLYMER AND PROCESS FOR PRODUCING VINYLAROMATIC POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-02-28 EP disclosed