Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LTA | P01374 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | RAD1 | O60671 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850783 | 0.89 | P2RY6 (0.37) | P2RY6MIFPNMTKDM4EUSP2 | |
| SCHEMBL1970565 | 0.82 | P2RY6 (0.37) | P2RY6MIFPNMTKDM4EUSP2 | |
| SCHEMBL30298625 | 0.82 | P2RY6 (0.37) | P2RY6MIFPNMTKDM4EUSP2 | |
| SCHEMBL11000954 | 0.73 | PNMT (0.34) | P2RY6MIFPNMTKDM4EUSP2 | |
| SCHEMBL10451237 | 0.72 | MAPK1 (0.43) | CYP3A4TDP1 | |
| SCHEMBL11000092 | 0.72 | P2RY6 (0.32) | P2RY6MIFPNMTKDM4EUSP2 | |
| SCHEMBL9428400 | 0.71 | P2RY6 (0.37) | P2RY6MIFPNMTKDM4EUSP2 | |
| SCHEMBL11001363 | 0.70 | MAPT (0.47) | KDM4EALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL6442271 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL9058554 | 0.68 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042533-B1 | SUBSTITUTED BENZOYL(THIO) UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0042533-A1 | Substituted benzoyl(thio) ureas, processes for their production and their use as pesticides | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |