Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452077 | 0.95 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL10694689 | 0.95 | CNR2 (0.43) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL15862682 | 0.91 | CYP2C9 (0.46) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL11157668 | 0.89 | CNR2 (0.43) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL11159272 | 0.89 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL11160153 | 0.89 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL14635509 | 0.89 | PGR (0.41) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL10450998 | 0.88 | ALDH1A1 (0.50) | LMNAALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL10452078 | 0.87 | KMT2A (0.43) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL10451133 | 0.85 | KMT2A (0.49) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266725-A1 | 4-cyano-4-(fluorophenyl)-3-(substituted phenyl) butyric acids, esters and derivatives thereof, and a method of selectively controlling undesirable vegetation in rice therewith | AMERICAN CYANAMID COMPANY (US) | 1988-05-11 | — | — | EP | claimed |
| EP-2731933-B1 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-9084425-B2 | 2,3-diphenyl-valeronitrile derivatives, method for the production thereof and use thereof as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-21 | — | — | US | disclosed |
| US-20140235446-A1 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
| EP-2731933-A2 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer Intellectual Property GmbH (DE) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013010882-A2 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |
| US-4898609-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0266725-A1 | 4-cyano-4-(fluorophenyl)-3-(substituted phenyl) butyric acids, esters and derivatives thereof, and a method of selectively controlling undesirable vegetation in rice therewith | AMERICAN CYANAMID COMPANY (US) | 1988-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235446-A1 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | DDT, CYP1A1, CYP4Z1 | LMNA 3069/4885SMN1; SMN2 4428/4885ALDH1A1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.