Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 6/20 | 0.57 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051087 | 0.81 | LMNA (0.52) | BPTFLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2614925 | 0.79 | BPTF (0.55) | BPTFNOS3NOS2LMNASMN1; SMN2 | |
| SCHEMBL9432808 | 0.77 | LMNA (0.70) | BPTFLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27776507 | 0.75 | SDHB (0.54) | BPTFLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15722708 | 0.75 | PIK3C3 (0.47) | — | |
| SCHEMBL7754155 | 0.74 | LMNA (0.45) | BPTFLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6296316 | 0.72 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL10519534 | 0.72 | NOS3 (0.50) | BPTFNOS3NOS2LMNASMN1; SMN2 | |
| SCHEMBL12859521 | 0.72 | NUDT1 (0.59) | BPTFSMN1; SMN2GAAMAPTCYP3A4 | |
| SCHEMBL4915813 | 0.70 | NOS3 (0.60) | NOS3NOS2LMNASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101613322-A | One class contains the synthetic and weeding activity of the chiral aryloxy phenoxy propionic acid ester derivative of pyrimidine | UNIV HUAZHONG NORMAL | 2009-12-30 | — | — | CN | disclosed |
| US-4980510-A | REACTING A SUBSTITUTED HALOBENZENE WITH SODIUM HYDROSULFIDE OR SODIUM SULFIDE AND ACIDIFICATION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0302312-A2 | Aryloxy (or thio)-aminopyrimidines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302321-A2 | Process for the preparation of thiophenols, and these thiophenols | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |