Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452830 | 0.89 | TBXA2R (0.61) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL10452836 | 0.88 | TBXA2R (0.62) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL10453024 | 0.86 | TBXA2R (0.58) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL10452733 | 0.86 | TBXA2R (0.60) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL10453021 | 0.83 | ALDH1A1 (0.59) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL25265635 | 0.79 | POLB (0.49) | MEN1KMT2A | |
| SCHEMBL10451941 | 0.79 | RAB9A (0.55) | TBXA2RMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL10453042 | 0.79 | ALDH1A1 (0.49) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL10452827 | 0.78 | ALDH1A1 (0.54) | TBXA2RMEN1KMT2ATBXAS1PRMT1 | |
| SCHEMBL10452821 | 0.78 | TAAR1 (0.57) | TBXA2RMEN1KMT2ATBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |