Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451941 | 0.91 | RAB9A (0.55) | ALDH1A1MAPTTBXA2RLSSMEN1 | |
| SCHEMBL10452827 | 0.91 | ALDH1A1 (0.54) | ALDH1A1MAPTTBXA2RLSSMEN1 | |
| SCHEMBL10452830 | 0.90 | TBXA2R (0.61) | ALDH1A1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL10452821 | 0.90 | TAAR1 (0.57) | ALDH1A1MAPTTBXA2RLSSMEN1 | |
| SCHEMBL10453024 | 0.87 | TBXA2R (0.58) | ALDH1A1MAPTTBXA2RLSSMEN1 | |
| SCHEMBL10453021 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TBXA2RMEN1KMT2APRMT1 | |
| SCHEMBL10451939 | 0.81 | AKR1C3 (0.55) | ALDH1A1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL10452720 | 0.79 | NPSR1 (0.46) | ALDH1A1KMT2ACA1CA2RAB9A | |
| SCHEMBL10453026 | 0.79 | TBXA2R (0.59) | ALDH1A1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL10452731 | 0.77 | NSD2 (0.48) | ALDH1A1MAPTKMT2AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |