Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452830 | 0.93 | TBXA2R (0.61) | ALDH1A1TP53GAATBXA2RTBXAS1 | |
| SCHEMBL10453024 | 0.90 | TBXA2R (0.58) | ALDH1A1TP53GAATBXA2RTBXAS1 | |
| SCHEMBL9813854 | 0.84 | KMT2A (0.44) | ALDH1A1TP53GAATBXA2RMEN1 | |
| SCHEMBL10451941 | 0.83 | RAB9A (0.55) | ALDH1A1TBXA2RMEN1KMT2A | |
| SCHEMBL10453042 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9813834 | 0.83 | KMT2A (0.43) | ALDH1A1TP53GAATBXA2RMEN1 | |
| SCHEMBL10452827 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL10453026 | 0.83 | TBXA2R (0.59) | ALDH1A1TP53GAATBXA2RTBXAS1 | |
| SCHEMBL10452821 | 0.82 | TAAR1 (0.57) | ALDH1A1GAATBXA2RTBXAS1MEN1 | |
| SCHEMBL10451939 | 0.81 | AKR1C3 (0.55) | ALDH1A1TP53TBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |