Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528930 | 0.82 | TSHR (0.49) | MAPTCA2MMP1MMP2MMP9 | |
| SCHEMBL9528936 | 0.82 | TSHR (0.49) | MAPTCA2MMP1MMP2MMP9 | |
| SCHEMBL10452498 | 0.80 | NOS3 (0.46) | CA1CA2NOS3NOS1CYP19A1 | |
| SCHEMBL9530547 | 0.80 | MEN1 (0.48) | NOS3NOS1MAOAMAOBALDH1A1 | |
| SCHEMBL9530548 | 0.80 | MEN1 (0.48) | NOS3NOS1MAOAMAOBALDH1A1 | |
| SCHEMBL9527879 | 0.78 | IDO1 (0.47) | MAPTCA1CA2NOS3NOS1 | |
| SCHEMBL10453547 | 0.76 | NOS3 (0.47) | MAPTNOS3NOS1CYP19A1MAOA | |
| SCHEMBL10453549 | 0.76 | NOS3 (0.47) | MAPTNOS3NOS1CYP19A1MAOA | |
| SCHEMBL10453553 | 0.76 | RORC (0.49) | MAPTRORCCA1CA2MAOA | |
| SCHEMBL10453552 | 0.76 | RORC (0.49) | MAPTRORCCA1CA2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |