Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453553 | 1.00 | RORC (0.49) | RORCF2PRSS1PRSS2PRSS3 | |
| SCHEMBL10453766 | 0.81 | LMNA (0.50) | ALDH1A1MAPTKMT2AKDM1ACA12 | |
| SCHEMBL9528945 | 0.81 | LMNA (0.50) | ALDH1A1MAPTKMT2AKDM1ACA12 | |
| SCHEMBL10452497 | 0.79 | KDM1A (0.46) | ALDH1A1MAPTKMT2ASAE1UBA2 | |
| SCHEMBL10452496 | 0.79 | KDM1A (0.46) | ALDH1A1MAPTKMT2ASAE1UBA2 | |
| SCHEMBL9530551 | 0.78 | RORC (0.44) | RORCALDH1A1KMT2ASAE1UBA2 | |
| SCHEMBL10453544 | 0.78 | RORC (0.47) | RORCF2PRSS1PRSS2PRSS3 | |
| SCHEMBL9530625 | 0.76 | MAOA (0.44) | RORCALDH1A1KMT2ASAE1UBA2 | |
| SCHEMBL10453554 | 0.76 | MAPT (0.44) | RORCALDH1A1MAPTARMAOA | |
| SCHEMBL10453550 | 0.73 | NOS3 (0.44) | ALDH1A1MAPTKMT2ASAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |