Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 7/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455805 | 0.82 | S1PR5 (0.42) | EPHX2ATMKMT2AS1PR5 | |
| SCHEMBL10455517 | 0.82 | KMT2A (0.42) | EPHX2ELANEDGAT1FAAHKMT2A | |
| SCHEMBL10455484 | 0.82 | KMT2A (0.42) | EPHX2ELANEDGAT1FAAHKMT2A | |
| SCHEMBL10454525 | 0.82 | KMT2A (0.53) | ACSL1EPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455781 | 0.81 | ELANE (0.57) | ACSL1EPHX2ELANEDGAT1FAAH | |
| SCHEMBL10454504 | 0.81 | ELANE (0.43) | ACSL1EPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455778 | 0.81 | RORC (0.38) | ACSL1EPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455809 | 0.79 | EPHX2 (0.43) | ACSL1EPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455506 | 0.76 | S1PR5 (0.40) | ELANEKMT2AS1PR5 | |
| SCHEMBL10455806 | 0.75 | ELANE (0.45) | EPHX2ELANEFAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |