Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721344 | 0.80 | CA1 (0.38) | CA1CA2BCL2BCL2L1MCL1 | |
| SCHEMBL9721310 | 0.72 | CYP3A4 (0.35) | CA1CA2NUAK1IGF1RMET | |
| SCHEMBL9721418 | 0.72 | CA1 (0.36) | CA1CA2 | |
| SCHEMBL10454966 | 0.70 | CYP3A4 (0.35) | CA1CA2NUAK1IGF1RMET | |
| SCHEMBL19126271 | 0.66 | CA1 (0.78) | CA1CA2 | |
| SCHEMBL9721307 | 0.64 | ERN1 (0.38) | CA1CA2 | |
| SCHEMBL9721279 | 0.64 | CA1 (0.46) | CA1CA2SRC | |
| SCHEMBL9721303 | 0.64 | SELL (0.37) | KDRBCL2BCL2L1MCL1BCL2L2 | |
| SCHEMBL10453709 | 0.62 | TSHR (0.35) | SRCKDR | |
| SCHEMBL7929083 | 0.62 | CA1 (0.54) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | disclosed |