Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721269 | 0.75 | SENP1 (0.36) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9721390 | 0.71 | TLR8 (0.43) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9721271 | 0.70 | APP (0.48) | KDM4EALDH1A1MAPTHPGDTRPA1 | |
| SCHEMBL9721316 | 0.70 | ERN1 (0.39) | CASP1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7873560 | 0.70 | KDM4E (0.50) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL47861 | 0.70 | TSHR (0.56) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL26437113 | 0.68 | CYP1A2 (0.55) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL31344493 | 0.67 | HSD17B1 (0.59) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL31212445 | 0.67 | HSD17B1 (0.59) | TSHRCASP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9721292 | 0.66 | HSD17B1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | claimed |