Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RGS17 | Q9UGC6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721345 | 0.87 | ACHE (0.38) | CYP3A4SENP1 | |
| SCHEMBL9721344 | 0.81 | CA1 (0.38) | BCL2L1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL24936683 | 0.71 | SELL (0.40) | SELLSELPSELEBCL2L1KDM4E | |
| SCHEMBL24923348 | 0.71 | SELL (0.40) | SELLSELPSELEBCL2L1KDM4E | |
| SCHEMBL9721279 | 0.70 | CA1 (0.46) | MEN1ALDH1A1MAPTKMT2APTGS1 | |
| SCHEMBL9721281 | 0.70 | CA1 (0.37) | SENP1 | |
| SCHEMBL9721312 | 0.70 | MAPK8 (0.34) | BCL2L1MAPK8KDM4EMEN1ALDH1A1 | |
| SCHEMBL25667109 | 0.69 | BCL2L1 (0.32) | SELLSELPSELEBCL2L1MEN1 | |
| SCHEMBL10454937 | 0.64 | CA1 (0.34) | BCL2L1BCL2MCL1BCL2L2KDR | |
| SCHEMBL25575178 | 0.64 | SENP1 (0.42) | SELLSELPSELEKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |