SCHEMBL8655669

SCHEMBL8655669

CCc1cc(C2c3ccccc3-c3ccccc32)c(CC)cc1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.37
EDNRB P24530 2/20 0.35
EDNRA P25101 2/20 0.35
ACHE P22303 2/20 0.34
BCHE P06276 1/20 0.34
TSHR P16473 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
MAPK1 P28482 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
GPR3 P46089 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455243 0.77 HTR2A (0.45) HTR2AACHEBCHECA1CA2
SCHEMBL832574 0.72 ALDH1A1 (0.43) CYP1A2ALDH1A1POLBMAPTNOS2
SCHEMBL7646509 0.70 GABRA1 (0.45) HTR2AACHEBCHECA1CA2
SCHEMBL3630933 0.68 ALDH1A1 (0.52) HTR2ATSHRCA1CA2GPR3
SCHEMBL5968553 0.68 MAPT (0.41) MAPK1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL11468902 0.68 AR (0.42) CYP1A2ALDH1A1POLBMAPTNOS2
SCHEMBL9778172 0.67 IDO1 (0.45) TSHRCYP1A2ALDH1A1POLBMAPT
SCHEMBL576611 0.67 SLC6A2 (0.42) HTR2AMAPK1CA1CA2ALDH1A1
SCHEMBL3366572 0.67 MEN1 (0.43) HTR2ACA1CA2POLBL3MBTL1
SCHEMBL16102287 0.66 CSNK2A2 (0.50) TSHRCYP1A2MAPK1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750641-A LIQUID CRYSTAL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-12 US disclosed