Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.42 |
| ▸ | CNR1 | P21554 | 9/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455645 | 0.88 | BTK (0.41) | S1PR5RAB9ARORC | |
| SCHEMBL10455787 | 0.85 | RORC (0.39) | S1PR5KMT2ARORC | |
| SCHEMBL10454493 | 0.85 | RORC (0.43) | S1PR5RORC | |
| SCHEMBL9765552 | 0.84 | RORC (0.41) | S1PR5RORC | |
| SCHEMBL10455483 | 0.84 | RORC (0.41) | S1PR5RORC | |
| SCHEMBL10455763 | 0.83 | RORC (0.41) | S1PR5CYP2C9RORC | |
| SCHEMBL10454502 | 0.82 | ACSL1 (0.43) | CNR2CNR1CDC25BMEN1KMT2A | |
| SCHEMBL9765545 | 0.81 | CNR2 (0.40) | CNR2CNR1CDC25B | |
| SCHEMBL9799893 | 0.81 | CNR2 (0.40) | CNR2CNR1CDC25B | |
| SCHEMBL9799899 | 0.80 | PYGL (0.36) | CNR2CNR1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |