Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455787 | 0.90 | RORC (0.39) | BTKRORCGRIK1GRIA2S1PR5 | |
| SCHEMBL10454493 | 0.90 | RORC (0.43) | BTKRORCGRIK1GRIA2S1PR5 | |
| SCHEMBL9765552 | 0.89 | RORC (0.41) | RORCGRIK1GRIA2S1PR5AKR1C3 | |
| SCHEMBL10455483 | 0.89 | RORC (0.41) | RORCGRIK1GRIA2S1PR5AKR1C3 | |
| SCHEMBL10455763 | 0.88 | RORC (0.41) | RORCGRIK1GRIA2S1PR5AKR1C3 | |
| SCHEMBL10455485 | 0.88 | CNR2 (0.42) | RORCRAB9AS1PR5 | |
| SCHEMBL10454526 | 0.88 | GRIK1 (0.47) | BTKRAB9AGRIK1GRIA2S1PR5 | |
| SCHEMBL10455774 | 0.84 | P2RX7 (0.43) | BTKRORCRAB9AGRIK1GRIA2 | |
| SCHEMBL10455761 | 0.84 | P2RX7 (0.43) | BTKRORCRAB9AGRIK1GRIA2 | |
| SCHEMBL10455519 | 0.84 | P2RX7 (0.43) | BTKRORCRAB9AGRIK1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |