Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455778 | 0.83 | RORC (0.38) | TDP1ALDH1A1LMNAKMT2AEPHX2 | |
| SCHEMBL10455487 | 0.83 | EPHX2 (0.39) | EPHX2FAAHDGAT1ELANE | |
| SCHEMBL10455503 | 0.81 | POLB (0.40) | MAPK1MAPTTDP1POLBNPSR1 | |
| SCHEMBL10455484 | 0.80 | KMT2A (0.42) | ALDH1A1KMT2AL3MBTL1EPHX2FAAH | |
| SCHEMBL10455517 | 0.80 | KMT2A (0.42) | ALDH1A1KMT2AL3MBTL1EPHX2FAAH | |
| SCHEMBL10454525 | 0.78 | KMT2A (0.53) | POLBKMT2AEPHX2FAAHDGAT1 | |
| SCHEMBL10454523 | 0.77 | MAPT (0.54) | MAPK1MAPTTDP1POLBNPSR1 | |
| SCHEMBL10455473 | 0.77 | KMT2A (0.44) | MAPK1MAPTPOLBNPSR1GAA | |
| SCHEMBL10455809 | 0.75 | EPHX2 (0.43) | TDP1POLBALDH1A1LMNAEPHX2 | |
| SCHEMBL10454495 | 0.75 | RORC (0.40) | MAPK1MAPTTDP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |