Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27050826 | 0.83 | KDM4E (0.38) | OPRK1KMT2AKDM4EMAPK1GAA | |
| SCHEMBL31120928 | 0.81 | CYP1A2 (0.39) | KMT2AKDM4EMAPK1LMNATP53 | |
| SCHEMBL806473 | 0.81 | CYP1A2 (0.39) | KMT2AKDM4EMAPK1LMNATP53 | |
| SCHEMBL9483980 | 0.81 | IDO1 (0.39) | KDM4EMAPK1LMNAALDH1A1CYP3A4 | |
| SCHEMBL23218588 | 0.74 | ALOX15 (0.33) | KDM4EGAAALDH1A1ALOX15HTT | |
| SCHEMBL6948759 | 0.74 | RARA (0.33) | KMT2ALMNAALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5153438 | 0.74 | HTR2A (0.35) | ALDH1A1CYP1A2 | |
| SCHEMBL24752718 | 0.74 | CYP3A4 (0.33) | KDM4ELMNATP53ALDH1A1CYP3A4 | |
| SCHEMBL28792295 | 0.74 | CA3 (0.38) | KDM4EKCNA3 | |
| SCHEMBL23087388 | 0.74 | CYP3A4 (0.39) | KDM4EMAPK1LMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2024-07-18 | — | — | US | disclosed |
| EP-4310077-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-4906658-A | Fluoro-sulfones | MERCK FROSST CANADA, INC. (CA) | 1990-03-06 | — | — | US | disclosed |
| EP-0288202-A2 | Fluoro-sulfones | MERCK FROSST CANADA INC. (CA) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239761-A1 | BICYCLIC PHENOL COMPOUNDS AND USE THEREOF | CYP3A43, CYP11B2, UGT2B7 | OPRK1 575/4885KMT2A 2972/4885KDM4E 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.