Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.65 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457449 | 0.87 | APP (0.59) | APPLTA4HALDH1A1 | |
| SCHEMBL3031836 | 0.86 | NR5A1 (0.62) | APPLTA4HNR5A1DRD2DRD4 | |
| SCHEMBL226548 | 0.85 | LTA4H (0.64) | APPLTA4HNR5A1ESR1CYP19A1 | |
| SCHEMBL274829 | 0.83 | ALDH1A1 (0.62) | APPLTA4HNR5A1ALDH1A1ESR1 | |
| SCHEMBL2473527 | 0.82 | LTA4H (0.68) | APPLTA4HNR5A1ESR1ESR2 | |
| SCHEMBL2470706 | 0.82 | NR5A1 (0.75) | LTA4HNR5A1ESR1ESR2DRD2 | |
| SCHEMBL4448744 | 0.81 | LTA4H (0.61) | APPLTA4HNR5A1ALDH1A1ESR1 | |
| SCHEMBL1437186 | 0.81 | CYP19A1 (0.70) | LTA4HNR5A1ESR1CYP19A1ESR2 | |
| SCHEMBL10458215 | 0.80 | APP (0.53) | APPALDH1A1 | |
| SCHEMBL1859432 | 0.80 | LTA4H (0.52) | APPLTA4HNR5A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |
| EP-0091598-B1 | FLUORO-ETHOXYPHENYL-(DI)-THIOPHOSPHORIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | claimed |
| EP-0091598-A2 | Fluoro-ethoxyphenyl-(di)-thiophosphoric-acid esters, process for their preparation and their use as pesticides | BASF Aktiengesellschaft (DE) | 1983-10-19 | — | — | EP | claimed |
| EP-3581565-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | Beijing Zhibo Bio-Medical Technology Co., Ltd. (CN) | 2019-12-18 | — | — | EP | disclosed |
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | ZHANG ZHIYONG (CN) | 2017-02-09 | — | — | US | disclosed |
| CN-103724207-B | Phenylbenzyl ether derivative and its preparation method and application | 北京智博高科生物技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
| US-9260400-B2 | I-arylpiperazinic ligands of 5-HT7 receptor and use thereof | UNIVERSITA' DEGLI STUDI DI BARI “ALDO MORO” (IT) | 2016-02-16 | — | — | US | disclosed |
| EP-2816037-A2 | New 1-arylpiperazinic ligands of 5-HT7 receptor and use thereof | Università degli Studi di Bari "Aldo Moro" (IT) | 2014-12-24 | — | — | EP | disclosed |
| US-20140086834-A1 | NEW I-ARYLPIPERAZINIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF | UNIVERSITA' DEGLI STUDI DI BARI ''ALDO MORO'' (IT) | 2014-03-27 | — | — | US | disclosed |
| WO-2012159662-A1 | NEW 1-ARYLPIPERAZINIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF | UNIVERSITA' DEGLI STUDI DI BARI (IT) | 2012-11-29 | — | — | WO | disclosed |
| US-4552894-A | INSECTICIDE, MITICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4551448-A | INSECTICIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0091598-B1 | FLUORO-ETHOXYPHENYL-(DI)-THIOPHOSPHORIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0091598-A2 | Fluoro-ethoxyphenyl-(di)-thiophosphoric-acid esters, process for their preparation and their use as pesticides | BASF Aktiengesellschaft (DE) | 1983-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | APP, PSEN1, PSEN2 | APP 1/4885LTA4H 3473/4885NR5A1 1357/4885 |
| US-20140086834-A1 | NEW I-ARYLPIPERAZINIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF | HTR7, HTR2C, HTR5A | APP 2418/4885LTA4H 1230/4885NR5A1 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.