Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10460538 | 0.97 | MAOB (0.49) | MAOBHTR2AMAOAMAPT | |
| Oxalic Acid SCHEMBL10459285 | 0.89 | HTR2A (0.49) | HTR2ADRD3MAPT | |
| SCHEMBL10556431 | 0.88 | HTR2A (0.47) | HTR2AUSP2HTR1ADRD2DRD1 | |
| SCHEMBL10560816 | 0.84 | HRH2 (0.58) | HTR2ACYP2D6HRH1 | |
| SCHEMBL10461368 | 0.83 | PAX8 (0.59) | MAOBMAOAKCNH2 | |
| SCHEMBL7320146 | 0.83 | ABCB11 (0.61) | HTR2AKCNH2HTR1AADRA2ADRD2 | |
| SCHEMBL10558384 | 0.83 | HTR2A (0.53) | HTR2AUSP2HTR1ADRD2DRD1 | |
| Hydrochloric Acid SCHEMBL10459192 | 0.83 | PAX8 (0.58) | MAOBMAOAKCNH2 | |
| SCHEMBL10461614 | 0.82 | HTR2A (0.47) | MAOBHTR2AUSP2HTR1ADRD2 | |
| SCHEMBL10460536 | 0.81 | HTR2A (0.58) | HTR2AUSP2HTR1ADRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | claimed |