Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 6/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192159 | 0.82 | GSK3B (0.39) | GSK3BALDH1A1NPC1LMNAGAA | |
| SCHEMBL11931575 | 0.72 | GSK3B (0.41) | GSK3BALDH1A1HTTSMN1; SMN2CDK2 | |
| SCHEMBL14545936 | 0.71 | LRRK2 (0.36) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL14545929 | 0.70 | CDK2 (0.43) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL14542953 | 0.69 | CHEK1 (0.73) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL14545930 | 0.68 | CHEK1 (0.34) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL16535004 | 0.66 | KDM5A (0.67) | GSK3BALDH1A1LMNAGAAMAPT | |
| SCHEMBL7545686 | 0.65 | KDM4E (0.57) | GSK3BALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL16534447 | 0.64 | KDM5A (0.39) | GSK3BALDH1A1NPC1MAPTHTT | |
| SCHEMBL13993121 | 0.64 | CDK2 (0.62) | GSK3BALDH1A1NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908056-A | Herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-13 | — | — | US | disclosed |
| US-4838925-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0244166-A2 | Heterocyclic acetyl sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |