Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18137288 | 0.79 | ALDH1A1 (0.39) | CTSBMAPTALDH1A1GPR35MEN1 | |
| SCHEMBL30076339 | 0.78 | MAPT (0.49) | CTSBCDK1CCNB1MAPTALDH1A1 | |
| SCHEMBL28991131 | 0.78 | MAPT (0.49) | CTSBCDK1CCNB1MAPTALDH1A1 | |
| SCHEMBL4743474 | 0.74 | MAPT (0.44) | PSMB8CTSBGSK3AGSK3BCCNB2 | |
| SCHEMBL8022630 | 0.74 | PSMB8 (0.57) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL8034068 | 0.74 | PSMB8 (0.49) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL1044855 | 0.72 | PSMB8 (0.34) | PSMB8GSK3AGSK3BCCNB2CDK1 | |
| SCHEMBL18137287 | 0.68 | DYRK1A (0.36) | CTSBGSK3AGSK3BCDK1CCNB1 | |
| SCHEMBL31215568 | 0.68 | RIPK1 (0.52) | MAPTALDH1A1KMT2APOLBHTT | |
| SCHEMBL4363348 | 0.66 | GPR35 (0.60) | CTSBMAPTALDH1A1GPR35ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932365-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-10-05 | — | — | US | disclosed |
| US-9689868-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2017-06-27 | — | — | US | disclosed |
| EP-2626703-B1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORP (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170016888-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-01-19 | — | — | US | disclosed |
| EP-2269064-B1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORP (US) | 2016-11-30 | — | — | EP | disclosed |
| US-9459249-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| EP-2626703-A1 | Protein labeling with cyanobenzothiazole conjugates | Promega Corporation (US) | 2013-08-14 | — | — | EP | disclosed |
| EP-2269064-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009142678-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORPORATIN (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | QPCTL, BCAT1, QPCT | PSMB8 1583/4885CTSB 2667/4885GSK3A 4364/4885 |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | QPCTL, BCAT1, QPCT | PSMB8 1583/4885CTSB 2667/4885GSK3A 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.