Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AOC2 | O75106 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971764 | 0.86 | NR1H4 (0.49) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL8340038 | 0.82 | GAA (0.73) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL10464020 | 0.80 | MAPT (0.54) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL8971001 | 0.80 | GSR (0.41) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL8972254 | 0.78 | NR1H4 (0.51) | GAAALDH1A1TDP1KMT2A | |
| SCHEMBL8971750 | 0.75 | GAA (0.51) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL18459329 | 0.74 | CA2 (0.61) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL9575165 | 0.74 | GAA (0.70) | GAAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL11796135 | 0.73 | AOC2 (0.66) | GAAAOC2KMT2AAOC3MEN1 | |
| SCHEMBL10463196 | 0.72 | PTGS1 (0.56) | GAAALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906662-A | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0263229-A1 | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-04-13 | — | — | EP | disclosed |