Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763316 | 0.81 | ADRB2 (0.47) | — | |
| SCHEMBL9762641 | 0.80 | CCR5 (0.41) | MAOBPDK1TSHROPRK1DRD2 | |
| Bromide SCHEMBL9762763 | 0.78 | ADRB2 (0.43) | TSHROPRK1DRD2DRD3ALDH1A1 | |
| SCHEMBL9763274 | 0.76 | ADRB2 (0.39) | MAOBACHETSHROPRK1DRD2 | |
| SCHEMBL9763349 | 0.76 | ADRB2 (0.44) | PDK1TSHROPRK1DRD2DRD3 | |
| SCHEMBL9763673 | 0.75 | ADRB2 (0.40) | MAOBTSHROPRK1DRD2DRD3 | |
| SCHEMBL9763053 | 0.75 | ADRB2 (0.41) | MAOBTSHROPRK1DRD2DRD3 | |
| SCHEMBL25053635 | 0.74 | HDAC1 (0.48) | ACHELMNAHTTCYP2C9 | |
| SCHEMBL9763287 | 0.74 | ADRB2 (0.53) | TSHROPRK1DRD2DRD3CYP2C9 | |
| SCHEMBL9764542 | 0.73 | ADRB2 (0.41) | MAOBALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908386-A | Pharmaceuticals | GLAXO GROUP LIMITED (GB) | 1990-03-13 | — | — | US | disclosed |