Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107020 | 0.94 | AKR1C3 (0.60) | AKR1C3ALDH1A1MEP1BSMN1; SMN2HTT | |
| SCHEMBL7220855 | 0.87 | MEP1B (0.58) | AKR1C3ALDH1A1MEP1BSMN1; SMN2MAPT | |
| SCHEMBL10463119 | 0.86 | AKR1C3 (0.54) | AKR1C3ALDH1A1SMN1; SMN2MAPTRECQL | |
| SCHEMBL11106788 | 0.82 | AKR1C3 (0.68) | AKR1C3ALDH1A1MEP1BSMN1; SMN2HTT | |
| SCHEMBL7751590 | 0.82 | MEP1B (0.53) | AKR1C3ALDH1A1MEP1BSMN1; SMN2HTT | |
| SCHEMBL10460376 | 0.81 | RECQL (0.49) | AKR1C3ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL10462580 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HTTMAPTPOLB | |
| SCHEMBL10463281 | 0.80 | AKR1C3 (0.56) | AKR1C3ALDH1A1SMN1; SMN2MAPTRECQL | |
| SCHEMBL10462136 | 0.79 | RAB9A (0.53) | ALDH1A1SMN1; SMN2HTTSGMS1MAPT | |
| SCHEMBL10462371 | 0.79 | TBXA2R (0.59) | AKR1C3ALDH1A1SMN1; SMN2HTTSGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |