Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659280 | 0.85 | TBXA2R (0.70) | TBXA2RMEN1KMT2AAKR1C3TBXAS1 | |
| SCHEMBL10463756 | 0.84 | KMT2A (0.52) | L3MBTL1MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL11102786 | 0.83 | TBXA2R (0.71) | TBXA2RL3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL10867378 | 0.81 | ALDH1A1 (0.56) | TBXA2RL3MBTL1TBXAS1ALDH1A1MAPT | |
| SCHEMBL10462670 | 0.80 | GAA (0.50) | TBXA2RL3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL10462201 | 0.78 | ALDH1A1 (0.64) | TBXA2RTBXAS1PRMT1ALDH1A1MAPT | |
| SCHEMBL10462267 | 0.78 | TBXA2R (0.67) | TBXA2RMEN1KMT2AAKR1C3TBXAS1 | |
| SCHEMBL11339358 | 0.78 | TBXA2R (0.60) | TBXA2RMMP8MMP12MMP13TBXAS1 | |
| SCHEMBL8487453 | 0.77 | MMP8 (0.70) | TBXA2RMEN1KMT2AAKR1C3MMP8 | |
| SCHEMBL10460357 | 0.76 | AKR1C3 (0.63) | TBXA2RMEN1KMT2AAKR1C3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |