Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 7/20 | 0.70 |
| ▸ | MMP12 | P39900 | 7/20 | 0.70 |
| ▸ | MMP13 | P45452 | 7/20 | 0.70 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP7 | P09237 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170793 | 0.85 | MMP12 (0.82) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL11102786 | 0.82 | TBXA2R (0.71) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL4174812 | 0.80 | MMP8 (0.75) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL11339358 | 0.80 | TBXA2R (0.60) | MMP8MMP12MMP13TBXA2RHTT | |
| SCHEMBL10463307 | 0.77 | TBXA2R (0.50) | MMP8MMP12MMP13TBXA2RMEN1 | |
| SCHEMBL5321195 | 0.74 | TAAR1 (0.52) | PTGES2MEN1KMT2A | |
| SCHEMBL11105420 | 0.74 | MAPT (0.53) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL11105430 | 0.74 | MAPT (0.53) | MMP8MMP12MMP13MMP1MMP7 | |
| SCHEMBL27804764 | 0.73 | TAAR1 (0.48) | PTGES2MEN1KMT2A | |
| SCHEMBL8780612 | 0.73 | LMNA (0.55) | TBXA2RFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999005141-A1 | HISTAMINE H3 RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-02-04 | — | — | WO | disclosed |