Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463557 | 1.00 | PTGS2 (0.50) | PTGS2NUDT1KCNN3BPTFCSF1R | |
| SCHEMBL10464337 | 0.81 | GLP1R (0.44) | PTGS2BPTF | |
| SCHEMBL7024726 | 0.80 | NUDT1 (0.54) | PTGS2NUDT1KCNN3CSF1RIDH1 | |
| SCHEMBL10513282 | 0.78 | HTR7 (0.51) | PTGS2NUDT1PLK1 | |
| SCHEMBL11033911 | 0.77 | PPARA (0.49) | PTGS2BPTF | |
| SCHEMBL17560919 | 0.77 | NUDT1 (0.71) | NUDT1KCNN3EGFR | |
| SCHEMBL9788711 | 0.77 | NUDT1 (0.54) | PTGS2NUDT1KCNN3CSF1RIDH1 | |
| SCHEMBL10464914 | 0.75 | MEN1 (0.52) | PTGS2NUDT1KCNN3CSF1RIDH1 | |
| SCHEMBL10464913 | 0.75 | MEN1 (0.52) | PTGS2NUDT1KCNN3CSF1RIDH1 | |
| SCHEMBL14549610 | 0.74 | PTGS2 (0.66) | PTGS2BPTFCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4941910-A | 4-halo-2-oxy or sulfonyl-4-amino substituted pyrimidines as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |