Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464711 | 0.94 | TBXAS1 (0.50) | PDE3BPDE3ATBXAS1CRBNGRIN1 | |
| SCHEMBL10461647 | 0.89 | TBXAS1 (0.54) | PDE3BPDE3ATBXAS1CRBNGRIN1 | |
| SCHEMBL10461476 | 0.79 | TBXAS1 (0.55) | PDE3BPDE3ATBXAS1CRBNHTR1A | |
| SCHEMBL10463554 | 0.78 | TBXAS1 (0.57) | PDE3BPDE3ATBXAS1CRBNTNIK | |
| Hydrochloric Acid SCHEMBL10464252 | 0.78 | TBXAS1 (0.54) | PDE3BPDE3ATBXAS1CRBNHTR1A | |
| SCHEMBL10464344 | 0.76 | HTR1A (0.57) | PDE3BPDE3ATBXAS1CRBNHTR1A | |
| SCHEMBL10463487 | 0.75 | TBXAS1 (0.65) | PDE3BPDE3ATBXAS1CRBNTNIK | |
| SCHEMBL10463488 | 0.75 | TBXAS1 (0.65) | PDE3BPDE3ATBXAS1CRBNTNIK | |
| SCHEMBL10463789 | 0.75 | HTR1A (0.53) | PDE3BPDE3ATBXAS1CRBNHTR1A | |
| Acetic Acid SCHEMBL10463268 | 0.74 | TBXAS1 (0.52) | PDE3BPDE3ATBXAS1CRBNHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921862-A | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4792561-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |