Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194745 | 0.84 | ALDH1A1 (0.51) | SCDALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7016372 | 0.83 | SCD (0.61) | SCDALDH1A1LMNAMAPTGAA | |
| SCHEMBL20392523 | 0.79 | RAB9A (0.59) | SCDALDH1A1LMNAHPGDHTT | |
| SCHEMBL18398876 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNAHPGDNPSR1HTT | |
| SCHEMBL10464778 | 0.77 | GAA (0.57) | ALDH1A1LMNANPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL10591917 | 0.77 | RAB9A (0.76) | SCDALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL525660 | 0.76 | ALDH1A1 (0.54) | SCDALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL1820346 | 0.75 | ALDH1A1 (0.76) | ALDH1A1LMNAHPGDNPSR1HTT | |
| SCHEMBL10464271 | 0.74 | KMT2A (0.46) | SCDALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL13256497 | 0.74 | LMNA (0.48) | SCDALDH1A1LMNAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |