Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CTSD | P07339 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465055 | 0.86 | POLB (0.52) | HTTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10466119 | 0.84 | CTSD (0.47) | HTTCTSDALDH1A1POLBRAB9A | |
| SCHEMBL10466200 | 0.82 | POLB (0.67) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6325602 | 0.75 | SMN1; SMN2 (0.70) | HTTCTSDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8565487 | 0.69 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1NPSR1POLBRAB9A | |
| SCHEMBL8563635 | 0.68 | SMN1; SMN2 (0.80) | CYP1A2CYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| Bromide SCHEMBL8864660 | 0.68 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1NPSR1POLBRAB9A | |
| SCHEMBL9568271 | 0.68 | SMN1; SMN2 (0.86) | SMN1; SMN2ALDH1A1NPSR1POLB | |
| Hydrochloric Acid SCHEMBL8864540 | 0.68 | SMN1; SMN2 (0.78) | CYP1A2CYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| Bromide SCHEMBL8864504 | 0.67 | SMN1; SMN2 (0.84) | SMN1; SMN2ALDH1A1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | claimed |
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | disclosed |