Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772021 | 0.78 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL10465341 | 0.75 | PPARA (0.57) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL27615063 | 0.75 | KMT2A (0.68) | CYP1A2CYP2C19CYP2C9MAPTKMT2A | |
| SCHEMBL10554594 | 0.74 | PPARA (0.68) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL22221586 | 0.73 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL11077485 | 0.72 | ALDH1A1 (0.74) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL6157344 | 0.72 | PPARA (0.70) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL2625479 | 0.71 | KDM4E (0.64) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL9372364 | 0.70 | PPARA (0.72) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA | |
| SCHEMBL135713 | 0.70 | PPARA (0.72) | CYP1A2CYP3A4CYP2C19CYP2C9PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221014-A1 | Phenoxy compounds as microbicides | CIBA-GEIGY AG (CH) | 1987-05-06 | — | — | EP | disclosed |