Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10449482 | 1.00 | FPR2 (0.63) | FPR2PTPN1LDHAACESMN1; SMN2 | |
| SCHEMBL8412092 | 1.00 | FPR2 (0.63) | FPR2PTPN1LDHAACESMN1; SMN2 | |
| SCHEMBL10465688 | 0.91 | ACE (0.57) | FPR2PTPN1LDHAACESMN1; SMN2 | |
| SCHEMBL11828913 | 0.90 | PTPN1 (0.60) | FPR2PTPN1ACEHCRTR2GPR132 | |
| SCHEMBL7824676 | 0.90 | PTPN1 (0.60) | FPR2PTPN1ACEHCRTR2GPR132 | |
| SCHEMBL11320091 | 0.90 | PTPN1 (0.60) | FPR2PTPN1ACEHCRTR2GPR132 | |
| SCHEMBL3884012 | 0.88 | ACE (0.55) | FPR2PTPN1LDHAACESMN1; SMN2 | |
| SCHEMBL11862343 | 0.85 | CCR5 (0.55) | FPR2PTPN1ACEHPGDGPR132 | |
| SCHEMBL10807099 | 0.85 | ACE (0.55) | PTPN1ACEGPR132ITGB3ITGA2B | |
| SCHEMBL321226 | 0.84 | FPR2 (0.57) | FPR2PTPN1KMT2AHCRTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351382-B1 | Process for the synthesis of optically active aminoacids | MINI RICERCA SCIENT TECNOLOG (IT) | 1994-09-21 | — | — | EP | claimed |
| EP-0351382-A2 | Process for the synthesis of optically active aminoacids | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-01-17 | — | — | EP | claimed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0351382-B1 | Process for the synthesis of optically active aminoacids | MINI RICERCA SCIENT TECNOLOG (IT) | 1994-09-21 | — | — | EP | disclosed |
| EP-0498507-A1 | Process for the preparation of enantiomers of alpha-amino acid derivatives by asymmetric hydrogenation | DSM N.V. (NL) | 1992-08-12 | — | — | EP | disclosed |
| US-4912221-A | Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0357565-A2 | New process for the synthesis of the levodopa | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-03-07 | — | — | EP | disclosed |
| EP-0351382-A2 | Process for the synthesis of optically active aminoacids | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-01-17 | — | — | EP | disclosed |