Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465688 | 0.90 | ACE (0.57) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL14908475 | 0.86 | RAB9A (0.55) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL3884012 | 0.82 | ACE (0.55) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL3928164 | 0.82 | LNPEP (0.67) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL3928165 | 0.82 | LNPEP (0.67) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL7824676 | 0.82 | PTPN1 (0.60) | PTPN1ACEHCRTR2 | |
| SCHEMBL11320091 | 0.82 | PTPN1 (0.60) | PTPN1ACEHCRTR2 | |
| SCHEMBL11828913 | 0.82 | PTPN1 (0.60) | PTPN1ACEHCRTR2 | |
| SCHEMBL1793176 | 0.82 | GAA (0.76) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL31206887 | 0.82 | GAA (0.76) | GAARAB9AALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058642-A | HYPERTENSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-11-15 | — | — | US | disclosed |