Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469706 | 0.84 | MTNR1A (0.58) | — | |
| SCHEMBL4622573 | 0.83 | PPARD (0.53) | SIGMAR1KDM4CHTR6 | |
| SCHEMBL9521546 | 0.81 | HTR6 (0.44) | SIGMAR1KDM4CHTR6 | |
| SCHEMBL10467431 | 0.81 | ALDH1A1 (0.64) | HTR6 | |
| SCHEMBL10467993 | 0.81 | ALDH1A1 (0.46) | — | |
| SCHEMBL10467840 | 0.80 | SIGMAR1 (0.50) | SIGMAR1KDM4CHTR6 | |
| SCHEMBL4621036 | 0.79 | KDM4C (0.52) | SIGMAR1KDM4CHTR6 | |
| SCHEMBL4621230 | 0.79 | SIGMAR1 (0.53) | SIGMAR1KDM4C | |
| SCHEMBL4622233 | 0.77 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL1430487 | 0.77 | PPARD (0.69) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |