Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10466995 | 0.88 | KEAP1 (0.41) | KDM4CCHRNA7KEAP1NFE2L2KDM4E | |
| SCHEMBL10469441 | 0.85 | CHRNA7 (0.40) | SMN1; SMN2CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL10468561 | 0.84 | CISD1 (0.45) | KDM6BKDM4CSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10468582 | 0.84 | KDM6B (0.41) | KDM6BKDM4CSMN1; SMN2CHRNA7KDM4E | |
| SCHEMBL10469371 | 0.83 | KDM4E (0.43) | KDM6BKDM4CSMN1; SMN2CHRNA7KDM4E | |
| SCHEMBL10467363 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL10469372 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL10469476 | 0.82 | CHRNA7 (0.38) | SMN1; SMN2CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL10468700 | 0.80 | MIF (0.43) | SMN1; SMN2CHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL10468052 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2CHRNA7KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916229-A | Pyridine carboxylic acid derivates | WARNER-LAMBERT COMPANY (US) | 1990-04-10 | — | — | US | disclosed |