Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468052 | 0.90 | ALDH1A1 (0.40) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10468700 | 0.90 | MIF (0.43) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10469378 | 0.89 | PGK1 (0.38) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10467469 | 0.88 | CHRNA7 (0.36) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10468289 | 0.86 | SMN1; SMN2 (0.36) | CHRNA7SMN1; SMN2TLR7ALDH1A1KDM4E | |
| SCHEMBL10468610 | 0.86 | SMN1; SMN2 (0.38) | CHRNA7SMN1; SMN2TLR7ALDH1A1KDM4E | |
| SCHEMBL10468285 | 0.85 | KDM4E (0.38) | CHRNA7SMN1; SMN2TLR7ALDH1A1KDM4E | |
| SCHEMBL10469441 | 0.85 | CHRNA7 (0.40) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10468727 | 0.83 | HSP90AB1 (0.36) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10467486 | 0.82 | KDM6B (0.42) | CHRNA7SMN1; SMN2TLR7ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916229-A | Pyridine carboxylic acid derivates | WARNER-LAMBERT COMPANY (US) | 1990-04-10 | — | — | US | disclosed |