Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467363 | 0.89 | ALDH1A1 (0.47) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10467030 | 0.88 | PGK1 (0.38) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10469372 | 0.88 | ALDH1A1 (0.42) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10468342 | 0.85 | ESR1 (0.45) | ALDH1A1HSD17B10TDP1L3MBTL1CYP1A2 | |
| SCHEMBL10467486 | 0.85 | KDM6B (0.42) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10469476 | 0.85 | CHRNA7 (0.38) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10467364 | 0.84 | SMN1; SMN2 (0.40) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10468277 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10468696 | 0.84 | KDM4E (0.39) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14927568 | 0.81 | KEAP1 (0.39) | CHRNA7SMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916229-A | Pyridine carboxylic acid derivates | WARNER-LAMBERT COMPANY (US) | 1990-04-10 | — | — | US | disclosed |